Antibiotic Combinations Reduce Staphylococcus Aureus Clearance

The spread of antibiotic resistance has increased interest in combination-based treatments. Despite extensive research into the effects of drug combinations on bacterial growth, Much less is known about their effects on bacterial long-term clearance, particularly at cidal, clinically relevant concentrations. The authors systematically quantify Staphylococcus aureus survival during prolonged exposure…

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Community engagement: The Key to Tackling Antimicrobial Resistance (AMR) Across a One Health Context?

Antimicrobial resistance (AMR) is a One Health problem underpinned by complex drivers and behaviours. This is particularly so in low – and middle-income countries (LMICs), where social and systemic factors fuel (mis)use and drive AMR. Behavioural change around antimicrobial use could safeguard both existing and future treatments. However, changing behaviour…

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Public Knowledge, Practices, and Awareness of Antibiotics and Antibiotic Resistance in Myanmar: The First National Mobile Phone Panel Survey

Antimicrobial resistance is a global public health challenge. In 2015, World Health Organization urged all its member states to develop respective national action plans to curb this crisis. In response to this, the Ministry of Health and Sports, Myanmar, published the National Action Plan for Containment of AMR in Myanmar…

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The Importance of Antimicrobial Resistance in Medical Mycology

Prior to the SARS-CoV-2 pandemic, antibiotic resistance was identified as a major global health care concern. Although fungal infections remain largely unknown to the general public, total attributable annual deaths are comparable to or exceed global mortalities from malaria, tuberculosis, or HIV. The impact of fungal infections has been exacerbated…

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Safer Plant-Based Nanoparticles for Combating Antibiotic Resistance In Bacteria: A Comprehensive Review On Its Potential Applications, Recent Advances, And Future Perspective

The increasing issue of antibiotic resistance is a great challenge to the pharmaceutical industry. The pressure of developing newer, better compounds with capacity to kill or inhibit the growth of antibiotic resistant organisms is huge. In this direction, nanoparticles are gaining a lot of attention. For instance, the use of…

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Prevalence and Antimicrobial Resistance of Escherichia Coli in Chicken Meat and Edible Poultry Organs Collected from Retail Shops and Supermarkets of North Western Province in Sri Lanka

Escherichia coli (E. coli) is a bacterium that inhabits and colonize the guts of human beings and animals. Particular strains of this bacterium called ‘Shiga toxin-producing strains of E. coli’ (STECs) cause infections in humans due to the intake of food which is not cooked, partially cooked or contaminated with…

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Analysis of the Occurrence of Antibiotic Resistant Bacteria in the Hospital’s Effluent and its Receiving Environment

The use of antibiotics on a regular and excessive basis is a major factor in the spread of antibiotic-resistant bacteria. Patients discharge un-metabolized or relatively low doses of non-metabolized antibiotics through urine and stool, which might enter into the environment through sewage disposal and promote the emergence of antibiotic resistant…

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Time to Evaluate Decision Support Systems for Antimicrobial Prescribing Outside the Hospital

Computerised physician-order entry (CPOE) is a system where medical professional enter and send the treatment instructions and medications electronically instead of using paper chart method. computerised decision-support system (CDSS) is an application that helps healthcare providers in making therapeutic decisions, implement evidence- based clinical guidelines at the point- of- care.…

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Global Action on Antimicrobial Resistance: Lessons from the History of Climate Change And Tobacco Control Policy

Antimicrobial resistance is a public health threat that demands urgent action. AMR leads to reduced effectiveness of drugs like antibiotics resulting in milder and easily treatable infections turning to life-threatening conditions. AMR is increasing due to irrational use of antibiotics and hospital acquired secondary infections. In a recent commentary, experts…

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Antidepressants Promote the Spread of Extracellular Antibiotic Resistance Genes via Transformation

The unavoidable development of antibiotic resistance as a result of the use of antimicrobials is a major concern for human health. It is widely acknowledged that non-lethal antibiotic concentrations have accelerated the development and HGT process of antibiotic resistance. Compared to antibiotics, commonly prescribed non-antibiotic medications like antidepressants are also…

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