Residual Antimicrobial Agents in Food Originating from Animals

The use of antimicrobials, specifically antibiotics, is not limited to humans, but also common in animals and plants. However, the overuse of these antimicrobial agents has made the situation more worrisome. This means that misuse has led to mutations, gene transfers in microbes making them stronger to survive in the…

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Short Review on the Potential Alternatives to Antibiotics in the Era of Antibiotic Resistance

Antibiotics were once considered wonder drugs. They worked fantastically to treat infections and bring down the mortality and morbidity due to bacterial infections. Unfortunately, humans misused these drugs resulting in antibiotic resistance. As a result, antibiotics started to fail. Pharmaceutical companies are showing more interest in funding drugs like anticancer…

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A Synthetic Lipopeptide Targeting Top-Priority Multidrug-Resistant Gram-Negative Pathogens

Antimicrobial resistance is a major global health issue that requires immediate attention. Notably, multidrug-resistant (MDR) Pseudomonas aeruginosa, Acinetobacter baumannii, and Enterobacterales (e.g., Klebsiella pneumoniae) are major causes of morbidity and mortality. The World Health Organization (WHO) has identified these pathogens' carbapenem-resistant isolates as the top three priority pathogens for antibiotic…

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Enhancing Pharmacists’ Role in Developing Countries to Overcome the Challenge of Antimicrobial Resistance: A Narrative Review

Antimicrobial resistance (AMR) is a global health challenge and developing countries are more vulnerable to the adverse health impacts of AMR. Health care workers including pharmacists can play a key role to support the appropriate use of antimicrobials in developing countries and reduce AMR. Success stories of pharmacist-led programs in…

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Isolation and Characterization of Multidrug Resistance Bacteria from Hospital Sewage Samples, Maharashtra, India

Antibiotics are known as life saver drugs that can act against bacteria. However the increasing problem of antibiotic resistance (ABR) has raised an alarm and has even attracted the attention of the World Health Organization (WHO). As per the guidelines from WHO, many countries including India framed the National Action…

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New Antibiotics for Multidrug-Resistant Bacterial Strains: Latest Research Developments and Future Perspectives

Antibiotics are crown to the modern medicine, and they are the weapon against numerous infectious diseases. The exposure of bacteria to ‘non-lethal levels’ of antibiotics is causing antibiotic resistance (ABR) in them. Multidrug resistance (MDR) is the most common type of resistance. The MDR refers to bacteria showing resistance to…

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Antibiotic Resistance in Wild Birds
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Antibiotic Resistance in Wild Birds

Wild birds have been identified as sentinels, reservoirs, and potential antibiotic resistance spreaders. A variety of antibiotic-resistant bacteria have been discovered from wild bird species. Several investigations have found that resistant bacteria are transmitted to wild birds by human rest products. There is evidence that wild birds can spread resistant…

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A Hot Topic at the Environment–Health Nexus: Investigating the Impact of Climate Change on Infectious Diseases

The climate change affects the social, economic and environmental determinants of health. It is the ultimate challenge of our times. Climate change is projected to impact both endemicity and prevalence of infectious diseases. Pathogen distribution, particularly the geographic and temporal distribution of vector-borne diseases like dengue and malaria, is expected…

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Synthetic Antibacterial Minerals: Harnessing a Natural Geochemical Reaction to Combat Antibiotic Resistance

The misuse and overuse of antibiotics in livestock and clinical settings is increasing the natural selection of multidrug-resistant bacteria. The resultant is antibiotic resistance bacteria along with the rise in mortality and financial burden on livestock and the healthcare industry. Hence, there is a need for novel strategies to deal…

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Off-Label Use of Antibacterials in a Context of Antimicrobial Resistance Threat

One of the global challenges in the area of  health  is  antimicrobial  resistance,  and  it  is  urgent  to  rethink  the  use  of  antimicrobial  drugs. The use of clinical and epidemiological methods to analyze the potential benefits and risks of drug therapy  has now become  a  requirement  for  the  rational use…

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