Antibiotic Combinations Reduce Staphylococcus Aureus Clearance
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Antibiotic Combinations Reduce Staphylococcus Aureus Clearance

The spread of antibiotic resistance has increased interest in combination-based treatments. Despite extensive research into the effects of drug combinations on bacterial growth, Much less is known about their effects on bacterial long-term clearance, particularly at cidal, clinically relevant concentrations. The authors systematically quantify Staphylococcus aureus survival during prolonged exposure…

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November 17, 2022
The Importance of Antimicrobial Resistance in Medical Mycology
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The Importance of Antimicrobial Resistance in Medical Mycology

Prior to the SARS-CoV-2 pandemic, antibiotic resistance was identified as a major global health care concern. Although fungal infections remain largely unknown to the general public, total attributable annual deaths are comparable to or exceed global mortalities from malaria, tuberculosis, or HIV. The impact of fungal infections has been exacerbated…

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September 19, 2022
Analysis of the Occurrence of Antibiotic Resistant Bacteria in the Hospital’s Effluent and its Receiving Environment
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Analysis of the Occurrence of Antibiotic Resistant Bacteria in the Hospital’s Effluent and its Receiving Environment

The use of antibiotics on a regular and excessive basis is a major factor in the spread of antibiotic-resistant bacteria. Patients discharge un-metabolized or relatively low doses of non-metabolized antibiotics through urine and stool, which might enter into the environment through sewage disposal and promote the emergence of antibiotic resistant…

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August 30, 2022
Potentiating Hypoxic Microenvironment for Antibiotic Activation by Photodynamic Therapy to Combat Bacterial Biofilm Infections
ABR News

Potentiating Hypoxic Microenvironment for Antibiotic Activation by Photodynamic Therapy to Combat Bacterial Biofilm Infections

Biofilm is complex self-secreted matrix of bacteria composing polysaccharides, extracellular DNAs, and proteins that have adhered to surfaces, to create a biofilm. Biofilms enable the infection to persist, prevent the absorption of antimicrobials, and encourage drug resistance in bacteria, making it challenging to treat bacterial infections. The bacteria are immune…

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August 3, 2022
Natural Products And Their Semi-synthetic Derivatives Against Antimicrobial-resistant Human Pathogenic Bacteria and Fungi
ABR News

Natural Products And Their Semi-synthetic Derivatives Against Antimicrobial-resistant Human Pathogenic Bacteria and Fungi

Antibiotic resistance (ABR) is a global priority, like climate change. The issue of ABR in India is quadrupled due to injudicious antibiotic use in the human, animal and plant sectors, poor knowledge, underutilisation of diagnostic procedures, inadequate health facilities, overpopulation, and poverty. It is pertinent to address this issue because…

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July 27, 2022
Low-Cost Anti-Mycobacterial Drug Discovery Using Engineered E. Coli
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Low-Cost Anti-Mycobacterial Drug Discovery Using Engineered E. Coli

In the synthetic biology era, chemical genetics provides new tools for long-standing challenges in antimicrobial drug discovery. Microbial strains can be sensitised to drugs with specific mechanisms by making genetic changes to targeted functional pathways. High-throughput screening of these strains may then reveal new drugs that target the modified pathway…

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July 25, 2022
Understanding Antimicrobial Use in Subsistence Farmers in Chikwawa District Malawi, Implications for Public Awareness Campaigns
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Understanding Antimicrobial Use in Subsistence Farmers in Chikwawa District Malawi, Implications for Public Awareness Campaigns

Countries around the world have reported an increase in drug-resistant diseases over the past 20 years. This ramification is hampering human development and food security. The concept of climate change and antimicrobial resistance (AMR) is called "wicked policy challenges" by academics and policy actors because they arise from complex social…

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July 15, 2022
Antimicrobial Strategy for Targeted Elimination of Different Microbes, Including Bacterial, Fungal, and Viral Pathogens
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Antimicrobial Strategy for Targeted Elimination of Different Microbes, Including Bacterial, Fungal, and Viral Pathogens

The ongoing emergence of microbial pathogens for which no effective antimicrobials exist endangers global health, necessitating novel antimicrobial approaches. The bacterial pathogen Staphylococcus aureus (SA), particularly methicillin-resistant SA (MRSA), is a well-known multidrug-resistant pathogen. According to recent research, the photo-activated probe caused a structural change in the probe and conjugate…

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July 7, 2022
Antibiotic Residues in Milk: Control Strategies in Dairy Animals
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Antibiotic Residues in Milk: Control Strategies in Dairy Animals

The antibiotic resistance (AR) leads to the development of new resistant bacteria or superbugs, resulting in failure of antibiotic therapy under clinical situations in both humans and animals. AR development particularly in the pathogens has become the greatest threat to antibiotic therapy. Awareness and upgradation of knowledge regarding AR among…

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July 3, 2022
Antibiotic Resistance in the Drinking Water: Old and New Strategies to Remove Antibiotics, Resistant Bacteria, and Resistance Genes
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Antibiotic Resistance in the Drinking Water: Old and New Strategies to Remove Antibiotics, Resistant Bacteria, and Resistance Genes

Antibiotic resistance is a significant public health problem. It is a one health issue that requires immediate attention from various stakeholders. Being a one health issue, antibiotic resistance can be seen to be spreading across the human, animal, and environment domains. Drinking water is no exception. Various studies have identified…

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June 20, 2022