Antimicrobial resistance among uropathogens in the Asia-Pacific region: a systematic review

Urinary tract infections (UTIs) are common infections occurring in the community and hospitals. The treatment is usually empirical antibiotics like co-trimoxazole, ciprofloxacin, ceftriaxone, and nitrofurantoin. Nitrofurantoin and Fosfomycin are preferred oral antibiotics in many guidelines. Provisional antibiotic usage drives antimicrobial resistance (AMR). The Asia Pacific region (Southeast Asian countries and…

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Development of a Multifaceted Antimicrobial Stewardship Curriculum for Undergraduate Medical Education: The Antibiotic Stewardship, Safety, Utilization, Resistance, and Evaluation (ASSURE) Elective

Antibiotic stewardship (AS) is the effort to measure antibiotic misuse. The AS intent to improve antibiotic prescribing by clinicians and use by patients so that antibiotics are only prescribed and used when needed; to minimize misdiagnoses or delayed diagnoses leading to underuse of antibiotics; and to ensure that the right…

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Current Challenges and Future Opportunities of Phage Therapy

The discovery and introduction of antibiotics in clinical practice had revolutionized the field of modern medicine. However, the golden period of antibiotics has come to an end due to the injudicious use of antibiotics, the bacteria managed to develop multiple antibiotic resistance (ABR) mechanisms. ABR is a major public health…

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Environmental Hotspots for Antibiotic Resistance Genes

Misuse of antibiotics in humans, animals and plants lead to the development of antibiotic resistance. This phenomenon is not confined to humans or animals alone. Antibiotic resistance gets transferred between humans, animals, and the environment through antibiotic resistance genes. The soil and water contain diverse microbial communities. Antibiotic misuse coupled…

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Prevalence and Multidrug Resistance Pattern of Methicillin Resistant S. aureus Isolated from Frozen Chicken Meat in Bangladesh

The World Health Organization (WHO) characterizes food-borne diseases as “disease of infectious or toxic nature caused by consumption of food or water. Out of various food-borne pathogens, infections by Methicillin-resistant Staphylococcus aureus (MRSA) are continuously expanding within the community. Methicillin resistance in this bacterial species is very alarming for human…

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A descriptive analysis of antimicrobial resistance patterns of WHO priority pathogens isolated in children from a tertiary care hospital in India

The Global Action Plan is one of the key initiatives by the World Health Organization (WHO) to combat the increasing incidence of antimicrobial resistance (AMR). In this direction, WHO has articulated a list of pathogens under the umbrella of ‘priority pathogens’ to provide strategic direction to research and develop new…

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Novel tool to visualize antibiotic resistance

Detection of antibiotic resistance gene (ARGs) and antibiotic-resistant bacteria (ARB) have become of utmost importance to decide a line of treatment for any bacterial infection. As the evidence-based use of antibiotics will reduce the misuse of antibiotics, detection of antibiotic -resistance is currently under investigation. The presence of the enzyme…

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