The use of non-prescribed antibiotics; prevalence estimates in low-and-middle-income countries. A systematic review and meta-analysis

Self-medication and over the counter medication are very common practice in low- and middle-income countries (LMICs) like India. The use of antibiotics without prescription is enlisted among the most important causes of antibiotic resistance (ABR). The unwise and frequent consumption of non-prescribed antibiotics (NPA) is persisting in LMICs where a…

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Primary care physicians’ attitudes and perceptions towards antibiotic resistance and outpatient antibiotic stewardship in the USA: a qualitative study

About 30% of the antibiotics prescribed in the outpatient setting is unnecessary. This injudicious use of antibiotics could propel the emergence and spread of antibiotic resistance. Outpatient antibiotic stewardship is one of the ways to monitor antibiotic prescription practices. But what are the attitudes and perceptions of primary care physicians…

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Antibiotic resistance surveillance systems: A review

The twentieth century was the 'golden age' of antibiotics for the extensive development and its use in humans and animals. The idea behind the discovery of antibiotics was to reduce suffering and deaths due to curable infectious diseases. However, such immense use of antibiotics had let to the selection of…

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IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance

Antibiotic resistance has devastating socioeconomic impacts globally. A plethora of alternatives to antibiotics are under investigation. Moreover, antimicrobial strategies that are less likely to develop resistance are immediately required to treat severe antibiotic-resistant infections.   Recently, a team of researchers led by Joseph M. Salvino & Farokh Dotiwala (The Wistar…

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