COVID-19, pandemic has become a significant threat to global health and economy after Spanish influenza of early 20th century. The emergence of COVID-19 has consequences for development of Antimicrobial resistance (AMR). The COVID-19 outbreak crossed the international boarders so rapidly to become pandemic, may facilitate the spread of  antimicrobial resistance as it has been described as a problem that “knows no borders.” The current management practice of COVID-19 has potential implication, both positive and negative on AMR. During the current pandemic, the health care preparedness and management in the clinic, the social distancing, lock down, closing borders, reducing travels, increasing frequency of hand washing and using hand sanitizer along with the disinfectant cleaners outside the clinic and most importantly the public awareness has significant role on AMR.

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