Global Biogeography and Projection Of Soil Antibiotic Resistance Genes

It is a known fact that antibiotic resistance (ABR) is a multisectoral problem and to tackle it the approach also should be in multi directions which can be called a ‘one health’ approach. A systematic analysis has estimated that in 2019 globally around 4.95 million people lost their lives because…

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More than an Anthropogenic Phenomenon: Antimicrobial Resistance in Ungulates from Natural and Agricultural Environments

Antimicrobial resistance (AMR) has been recently acknowledged as one of the most pressing issues affecting human health and the role of mankind in exacerbating this problem with the overuse of antimicrobials is widely discussed. While causes of AMR has largely anthropogenic contributions, the fact that resistance against antimicrobials occurs naturally…

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Antibiotic Combinations Reduce Staphylococcus Aureus Clearance

The spread of antibiotic resistance has increased interest in combination-based treatments. Despite extensive research into the effects of drug combinations on bacterial growth, Much less is known about their effects on bacterial long-term clearance, particularly at cidal, clinically relevant concentrations. The authors systematically quantify Staphylococcus aureus survival during prolonged exposure…

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Community engagement: The Key to Tackling Antimicrobial Resistance (AMR) Across a One Health Context?

Antimicrobial resistance (AMR) is a One Health problem underpinned by complex drivers and behaviours. This is particularly so in low – and middle-income countries (LMICs), where social and systemic factors fuel (mis)use and drive AMR. Behavioural change around antimicrobial use could safeguard both existing and future treatments. However, changing behaviour…

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The Importance of Antimicrobial Resistance in Medical Mycology

Prior to the SARS-CoV-2 pandemic, antibiotic resistance was identified as a major global health care concern. Although fungal infections remain largely unknown to the general public, total attributable annual deaths are comparable to or exceed global mortalities from malaria, tuberculosis, or HIV. The impact of fungal infections has been exacerbated…

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Safer Plant-Based Nanoparticles for Combating Antibiotic Resistance In Bacteria: A Comprehensive Review On Its Potential Applications, Recent Advances, And Future Perspective

The increasing issue of antibiotic resistance is a great challenge to the pharmaceutical industry. The pressure of developing newer, better compounds with capacity to kill or inhibit the growth of antibiotic resistant organisms is huge. In this direction, nanoparticles are gaining a lot of attention. For instance, the use of…

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Prevalence and Antimicrobial Resistance of Escherichia Coli in Chicken Meat and Edible Poultry Organs Collected from Retail Shops and Supermarkets of North Western Province in Sri Lanka

Escherichia coli (E. coli) is a bacterium that inhabits and colonize the guts of human beings and animals. Particular strains of this bacterium called ‘Shiga toxin-producing strains of E. coli’ (STECs) cause infections in humans due to the intake of food which is not cooked, partially cooked or contaminated with…

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Analysis of the Occurrence of Antibiotic Resistant Bacteria in the Hospital’s Effluent and its Receiving Environment

The use of antibiotics on a regular and excessive basis is a major factor in the spread of antibiotic-resistant bacteria. Patients discharge un-metabolized or relatively low doses of non-metabolized antibiotics through urine and stool, which might enter into the environment through sewage disposal and promote the emergence of antibiotic resistant…

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Antidepressants Promote the Spread of Extracellular Antibiotic Resistance Genes via Transformation

The unavoidable development of antibiotic resistance as a result of the use of antimicrobials is a major concern for human health. It is widely acknowledged that non-lethal antibiotic concentrations have accelerated the development and HGT process of antibiotic resistance. Compared to antibiotics, commonly prescribed non-antibiotic medications like antidepressants are also…

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Natural Products And Their Semi-synthetic Derivatives Against Antimicrobial-resistant Human Pathogenic Bacteria and Fungi

Antibiotic resistance (ABR) is a global priority, like climate change. The issue of ABR in India is quadrupled due to injudicious antibiotic use in the human, animal and plant sectors, poor knowledge, underutilisation of diagnostic procedures, inadequate health facilities, overpopulation, and poverty. It is pertinent to address this issue because…

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