Global Action on Antimicrobial Resistance: Lessons from the History of Climate Change And Tobacco Control Policy
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Global Action on Antimicrobial Resistance: Lessons from the History of Climate Change And Tobacco Control Policy

Antimicrobial resistance is a public health threat that demands urgent action. AMR leads to reduced effectiveness of drugs like antibiotics resulting in milder and easily treatable infections turning to life-threatening conditions. AMR is increasing due to irrational use of antibiotics and hospital acquired secondary infections. In a recent commentary, experts…

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August 16, 2022
Antidepressants Promote the Spread of Extracellular Antibiotic Resistance Genes via Transformation
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Antidepressants Promote the Spread of Extracellular Antibiotic Resistance Genes via Transformation

The unavoidable development of antibiotic resistance as a result of the use of antimicrobials is a major concern for human health. It is widely acknowledged that non-lethal antibiotic concentrations have accelerated the development and HGT process of antibiotic resistance. Compared to antibiotics, commonly prescribed non-antibiotic medications like antidepressants are also…

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August 12, 2022
Potentiating Hypoxic Microenvironment for Antibiotic Activation by Photodynamic Therapy to Combat Bacterial Biofilm Infections
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Potentiating Hypoxic Microenvironment for Antibiotic Activation by Photodynamic Therapy to Combat Bacterial Biofilm Infections

Biofilm is complex self-secreted matrix of bacteria composing polysaccharides, extracellular DNAs, and proteins that have adhered to surfaces, to create a biofilm. Biofilms enable the infection to persist, prevent the absorption of antimicrobials, and encourage drug resistance in bacteria, making it challenging to treat bacterial infections. The bacteria are immune…

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August 3, 2022
Natural Products And Their Semi-synthetic Derivatives Against Antimicrobial-resistant Human Pathogenic Bacteria and Fungi
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Natural Products And Their Semi-synthetic Derivatives Against Antimicrobial-resistant Human Pathogenic Bacteria and Fungi

Antibiotic resistance (ABR) is a global priority, like climate change. The issue of ABR in India is quadrupled due to injudicious antibiotic use in the human, animal and plant sectors, poor knowledge, underutilisation of diagnostic procedures, inadequate health facilities, overpopulation, and poverty. It is pertinent to address this issue because…

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July 27, 2022
Low-Cost Anti-Mycobacterial Drug Discovery Using Engineered E. Coli
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Low-Cost Anti-Mycobacterial Drug Discovery Using Engineered E. Coli

In the synthetic biology era, chemical genetics provides new tools for long-standing challenges in antimicrobial drug discovery. Microbial strains can be sensitised to drugs with specific mechanisms by making genetic changes to targeted functional pathways. High-throughput screening of these strains may then reveal new drugs that target the modified pathway…

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July 25, 2022
Antimicrobial Resistance in the Globalized Food Chain: A One Health Perspective Applied to the Poultry Industry
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Antimicrobial Resistance in the Globalized Food Chain: A One Health Perspective Applied to the Poultry Industry

The food animal industry will face escalating challenges to increase productivity while minimizing AMR, since the global demand for animal protein has been continuously increasing and food animals play a key role in the global food supply, particularly broiler chickens. As chicken products are sources of low-cost, high-quality protein, poultry…

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July 19, 2022
Understanding Antimicrobial Use in Subsistence Farmers in Chikwawa District Malawi, Implications for Public Awareness Campaigns
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Understanding Antimicrobial Use in Subsistence Farmers in Chikwawa District Malawi, Implications for Public Awareness Campaigns

Countries around the world have reported an increase in drug-resistant diseases over the past 20 years. This ramification is hampering human development and food security. The concept of climate change and antimicrobial resistance (AMR) is called "wicked policy challenges" by academics and policy actors because they arise from complex social…

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July 15, 2022
Antimicrobial Strategy for Targeted Elimination of Different Microbes, Including Bacterial, Fungal, and Viral Pathogens
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Antimicrobial Strategy for Targeted Elimination of Different Microbes, Including Bacterial, Fungal, and Viral Pathogens

The ongoing emergence of microbial pathogens for which no effective antimicrobials exist endangers global health, necessitating novel antimicrobial approaches. The bacterial pathogen Staphylococcus aureus (SA), particularly methicillin-resistant SA (MRSA), is a well-known multidrug-resistant pathogen. According to recent research, the photo-activated probe caused a structural change in the probe and conjugate…

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July 7, 2022
Antibiotic Residues in Milk: Control Strategies in Dairy Animals
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Antibiotic Residues in Milk: Control Strategies in Dairy Animals

The antibiotic resistance (AR) leads to the development of new resistant bacteria or superbugs, resulting in failure of antibiotic therapy under clinical situations in both humans and animals. AR development particularly in the pathogens has become the greatest threat to antibiotic therapy. Awareness and upgradation of knowledge regarding AR among…

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July 3, 2022
Antibiotic Resistance in the Drinking Water: Old and New Strategies to Remove Antibiotics, Resistant Bacteria, and Resistance Genes
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Antibiotic Resistance in the Drinking Water: Old and New Strategies to Remove Antibiotics, Resistant Bacteria, and Resistance Genes

Antibiotic resistance is a significant public health problem. It is a one health issue that requires immediate attention from various stakeholders. Being a one health issue, antibiotic resistance can be seen to be spreading across the human, animal, and environment domains. Drinking water is no exception. Various studies have identified…

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June 20, 2022