Potentiating Hypoxic Microenvironment for Antibiotic Activation by Photodynamic Therapy to Combat Bacterial Biofilm Infections
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Potentiating Hypoxic Microenvironment for Antibiotic Activation by Photodynamic Therapy to Combat Bacterial Biofilm Infections

Biofilm is complex self-secreted matrix of bacteria composing polysaccharides, extracellular DNAs, and proteins that have adhered to surfaces, to create a biofilm. Biofilms enable the infection to persist, prevent the absorption of antimicrobials, and encourage drug resistance in bacteria, making it challenging to treat bacterial infections. The bacteria are immune…

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August 3, 2022
Natural Products And Their Semi-synthetic Derivatives Against Antimicrobial-resistant Human Pathogenic Bacteria and Fungi
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Natural Products And Their Semi-synthetic Derivatives Against Antimicrobial-resistant Human Pathogenic Bacteria and Fungi

Antibiotic resistance (ABR) is a global priority, like climate change. The issue of ABR in India is quadrupled due to injudicious antibiotic use in the human, animal and plant sectors, poor knowledge, underutilisation of diagnostic procedures, inadequate health facilities, overpopulation, and poverty. It is pertinent to address this issue because…

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July 27, 2022
Understanding Antimicrobial Use in Subsistence Farmers in Chikwawa District Malawi, Implications for Public Awareness Campaigns
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Understanding Antimicrobial Use in Subsistence Farmers in Chikwawa District Malawi, Implications for Public Awareness Campaigns

Countries around the world have reported an increase in drug-resistant diseases over the past 20 years. This ramification is hampering human development and food security. The concept of climate change and antimicrobial resistance (AMR) is called "wicked policy challenges" by academics and policy actors because they arise from complex social…

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July 15, 2022
Antimicrobial Strategy for Targeted Elimination of Different Microbes, Including Bacterial, Fungal, and Viral Pathogens
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Antimicrobial Strategy for Targeted Elimination of Different Microbes, Including Bacterial, Fungal, and Viral Pathogens

The ongoing emergence of microbial pathogens for which no effective antimicrobials exist endangers global health, necessitating novel antimicrobial approaches. The bacterial pathogen Staphylococcus aureus (SA), particularly methicillin-resistant SA (MRSA), is a well-known multidrug-resistant pathogen. According to recent research, the photo-activated probe caused a structural change in the probe and conjugate…

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July 7, 2022
Antibiotic Residues in Milk: Control Strategies in Dairy Animals
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Antibiotic Residues in Milk: Control Strategies in Dairy Animals

The antibiotic resistance (AR) leads to the development of new resistant bacteria or superbugs, resulting in failure of antibiotic therapy under clinical situations in both humans and animals. AR development particularly in the pathogens has become the greatest threat to antibiotic therapy. Awareness and upgradation of knowledge regarding AR among…

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July 3, 2022
Antibiotic Resistance in the Drinking Water: Old and New Strategies to Remove Antibiotics, Resistant Bacteria, and Resistance Genes
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Antibiotic Resistance in the Drinking Water: Old and New Strategies to Remove Antibiotics, Resistant Bacteria, and Resistance Genes

Antibiotic resistance is a significant public health problem. It is a one health issue that requires immediate attention from various stakeholders. Being a one health issue, antibiotic resistance can be seen to be spreading across the human, animal, and environment domains. Drinking water is no exception. Various studies have identified…

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June 20, 2022
Antimicrobial Resistance and One Health in the Post COVID-19 Era: What Should Health Students Learn?
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Antimicrobial Resistance and One Health in the Post COVID-19 Era: What Should Health Students Learn?

Antimicrobial resistance (AMR) is a critical worldwide health issue that jeopardizes our ability to fight illnesses. The onset of the COVID-19 pandemic has put the world in a shocking state. The pandemic exacerbated the problem of antimicrobial resistance, which was largely caused by irrational off-label use of antivirals, anthelmintics, antimalarials,…

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June 12, 2022
Antimicrobial Resistance in Antarctica: Is It Still A Pristine Environment?
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Antimicrobial Resistance in Antarctica: Is It Still A Pristine Environment?

Antimicrobial resistance (AMR) is a global public health threat. Surveillance is one of the critical interventions to tackle the emergence and spared of AMR. Antarctica is one such place where the human settlements are relatively less and acts as a simpler model to study the factors that increases AMR. There…

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June 6, 2022
Antibiotics in the Pipeline: A Literature Review (2017-2020)
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Antibiotics in the Pipeline: A Literature Review (2017-2020)

Antibiotic resistance (ABR) is causing increased mortality and morbidity and is straining the healthcare system. The rising problem of ABR can be controlled through effective antibiotic stewardship system and by facilitating new drug developments. Several new antibiotics are in the pipeline to fight the ABR pandemic. Most of these antibiotics…

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June 3, 2022
Impact of Antibiotics on Off-Target Infant Gut Microbiota and Resistance Genes in Cohort Studies
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Impact of Antibiotics on Off-Target Infant Gut Microbiota and Resistance Genes in Cohort Studies

nfants and young children are exposed to the most antibiotics of any age group, with an estimated 30–40% of children receiving at least one course of antibiotics during their first year of life. Although the majority of these antibiotics are used to treat acute respiratory tract infections, an unintended consequence…

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May 28, 2022