Impact of Antibiotics on Off-Target Infant Gut Microbiota and Resistance Genes in Cohort Studies
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Impact of Antibiotics on Off-Target Infant Gut Microbiota and Resistance Genes in Cohort Studies

nfants and young children are exposed to the most antibiotics of any age group, with an estimated 30–40% of children receiving at least one course of antibiotics during their first year of life. Although the majority of these antibiotics are used to treat acute respiratory tract infections, an unintended consequence…

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May 28, 2022
Residual Antimicrobial Agents in Food Originating from Animals
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Residual Antimicrobial Agents in Food Originating from Animals

The use of antimicrobials, specifically antibiotics, is not limited to humans, but also common in animals and plants. However, the overuse of these antimicrobial agents has made the situation more worrisome. This means that misuse has led to mutations, gene transfers in microbes making them stronger to survive in the…

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May 20, 2022
Short Review on the Potential Alternatives to Antibiotics in the Era of Antibiotic Resistance
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Short Review on the Potential Alternatives to Antibiotics in the Era of Antibiotic Resistance

Antibiotics were once considered wonder drugs. They worked fantastically to treat infections and bring down the mortality and morbidity due to bacterial infections. Unfortunately, humans misused these drugs resulting in antibiotic resistance. As a result, antibiotics started to fail. Pharmaceutical companies are showing more interest in funding drugs like anticancer…

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May 12, 2022
The Impact of Antimicrobial Resistance Awareness Interventions Involving Schoolchildren, Development of an Animation and Parents Engagements: A Pilot Study
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The Impact of Antimicrobial Resistance Awareness Interventions Involving Schoolchildren, Development of an Animation and Parents Engagements: A Pilot Study

Antimicrobial resistance (AMR) is a global health challenge, particularly in low- and middle-income countries where antibiotics are widely available to consumers, leading to their misuse. This study aimed to assess the potential of AMR animation and schoolchildren in influencing parents’ AMR knowledge, attitudes, and beliefs. A baseline surveys of parents…

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May 5, 2022
In-vitro Antimicrobial Activity of Lactuca Sativa Leaves against Isolated Clarithromycin-Resistant Superbugs
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In-vitro Antimicrobial Activity of Lactuca Sativa Leaves against Isolated Clarithromycin-Resistant Superbugs

One of the biggest discoveries in the year 1928 was the development of antibiotics. However as rightly mentioned by the discovery, Alexander Fleming himself, the misuse of antibiotics is making them less effective day by day. Due to mutations, the bacteria are gaining resistance and becoming smart enough to grow…

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May 4, 2022
A Synthetic Lipopeptide Targeting Top-Priority Multidrug-Resistant Gram-Negative Pathogens
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A Synthetic Lipopeptide Targeting Top-Priority Multidrug-Resistant Gram-Negative Pathogens

Antimicrobial resistance is a major global health issue that requires immediate attention. Notably, multidrug-resistant (MDR) Pseudomonas aeruginosa, Acinetobacter baumannii, and Enterobacterales (e.g., Klebsiella pneumoniae) are major causes of morbidity and mortality. The World Health Organization (WHO) has identified these pathogens' carbapenem-resistant isolates as the top three priority pathogens for antibiotic…

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April 19, 2022
Two New Drugs to Fight Superbugs Available on NHS Soon
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Two New Drugs to Fight Superbugs Available on NHS Soon

Antimicrobial resistance is a major issue which threatens to set modern medicine back to the pre-antibiotic era. Researchers estimate hard-to-treat infections already kill more than a million people per year globally. In this context world-leading innovations from United Kingdom are helping to develop two antibiotics which will save many lives. These…

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April 16, 2022
Implementing an Intervention to Reduce Use of Antibiotics for Suspected Urinary Tract Infection in Nursing Homes – A Qualitative Study of Barriers and Enablers Based on Normalization Process Theory
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Implementing an Intervention to Reduce Use of Antibiotics for Suspected Urinary Tract Infection in Nursing Homes – A Qualitative Study of Barriers and Enablers Based on Normalization Process Theory

It is an established fact that any antibiotic use contributes to the development of antibiotic resistance. In elderly care homes, urinary tract infections (UTI) are common. To treat these infections, antibiotics are used, with most prescriptions being inappropriate. There are many factors that influence the prescription practices of the doctor.…

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April 6, 2022
Gentamicin at Sub-Inhibitory Concentrations Selects for Antibiotic Resistance in the Environment
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Gentamicin at Sub-Inhibitory Concentrations Selects for Antibiotic Resistance in the Environment

The majority of antibiotics used in human medicine and animal production are excreted into the environment unmodified. Antibiotics discharged into the environment at low (sub-inhibitory) concentrations have the potential to select for antibiotic resistance, which might then spread to the human microbiome. Low-level anthropogenic sources of antibiotics would have a…

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April 3, 2022
Enhancing Pharmacists’ Role in Developing Countries to Overcome the Challenge of Antimicrobial Resistance: A Narrative Review
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Enhancing Pharmacists’ Role in Developing Countries to Overcome the Challenge of Antimicrobial Resistance: A Narrative Review

Antimicrobial resistance (AMR) is a global health challenge and developing countries are more vulnerable to the adverse health impacts of AMR. Health care workers including pharmacists can play a key role to support the appropriate use of antimicrobials in developing countries and reduce AMR. Success stories of pharmacist-led programs in…

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March 27, 2022