A Synthetic Lipopeptide Targeting Top-Priority Multidrug-Resistant Gram-Negative Pathogens
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A Synthetic Lipopeptide Targeting Top-Priority Multidrug-Resistant Gram-Negative Pathogens

Antimicrobial resistance is a major global health issue that requires immediate attention. Notably, multidrug-resistant (MDR) Pseudomonas aeruginosa, Acinetobacter baumannii, and Enterobacterales (e.g., Klebsiella pneumoniae) are major causes of morbidity and mortality. The World Health Organization (WHO) has identified these pathogens' carbapenem-resistant isolates as the top three priority pathogens for antibiotic…

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April 19, 2022
Two New Drugs to Fight Superbugs Available on NHS Soon
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Two New Drugs to Fight Superbugs Available on NHS Soon

Antimicrobial resistance is a major issue which threatens to set modern medicine back to the pre-antibiotic era. Researchers estimate hard-to-treat infections already kill more than a million people per year globally. In this context world-leading innovations from United Kingdom are helping to develop two antibiotics which will save many lives. These…

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April 16, 2022
Implementing an Intervention to Reduce Use of Antibiotics for Suspected Urinary Tract Infection in Nursing Homes – A Qualitative Study of Barriers and Enablers Based on Normalization Process Theory
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Implementing an Intervention to Reduce Use of Antibiotics for Suspected Urinary Tract Infection in Nursing Homes – A Qualitative Study of Barriers and Enablers Based on Normalization Process Theory

It is an established fact that any antibiotic use contributes to the development of antibiotic resistance. In elderly care homes, urinary tract infections (UTI) are common. To treat these infections, antibiotics are used, with most prescriptions being inappropriate. There are many factors that influence the prescription practices of the doctor.…

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April 6, 2022
Gentamicin at Sub-Inhibitory Concentrations Selects for Antibiotic Resistance in the Environment
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Gentamicin at Sub-Inhibitory Concentrations Selects for Antibiotic Resistance in the Environment

The majority of antibiotics used in human medicine and animal production are excreted into the environment unmodified. Antibiotics discharged into the environment at low (sub-inhibitory) concentrations have the potential to select for antibiotic resistance, which might then spread to the human microbiome. Low-level anthropogenic sources of antibiotics would have a…

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April 3, 2022
Enhancing Pharmacists’ Role in Developing Countries to Overcome the Challenge of Antimicrobial Resistance: A Narrative Review
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Enhancing Pharmacists’ Role in Developing Countries to Overcome the Challenge of Antimicrobial Resistance: A Narrative Review

Antimicrobial resistance (AMR) is a global health challenge and developing countries are more vulnerable to the adverse health impacts of AMR. Health care workers including pharmacists can play a key role to support the appropriate use of antimicrobials in developing countries and reduce AMR. Success stories of pharmacist-led programs in…

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March 27, 2022
Isolation and Characterization of Multidrug Resistance Bacteria from Hospital Sewage Samples, Maharashtra, India
ABR News

Isolation and Characterization of Multidrug Resistance Bacteria from Hospital Sewage Samples, Maharashtra, India

Antibiotics are known as life saver drugs that can act against bacteria. However the increasing problem of antibiotic resistance (ABR) has raised an alarm and has even attracted the attention of the World Health Organization (WHO). As per the guidelines from WHO, many countries including India framed the National Action…

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March 23, 2022
New Antibiotics for Multidrug-Resistant Bacterial Strains: Latest Research Developments and Future Perspectives
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New Antibiotics for Multidrug-Resistant Bacterial Strains: Latest Research Developments and Future Perspectives

Antibiotics are crown to the modern medicine, and they are the weapon against numerous infectious diseases. The exposure of bacteria to ‘non-lethal levels’ of antibiotics is causing antibiotic resistance (ABR) in them. Multidrug resistance (MDR) is the most common type of resistance. The MDR refers to bacteria showing resistance to…

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March 12, 2022
Governing Antimicrobial Resistance: A Narrative Review of Global Governance Mechanisms
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Governing Antimicrobial Resistance: A Narrative Review of Global Governance Mechanisms

Antimicrobial resistance (AMR), a central health challenge of the twenty first century, poses substantial population health risks, with deaths currently estimated to be around 700,000 per year globally. After implementing effective policy responses to AMR, with a Global Action Plan on AMR approved by the World Health Assembly in 2015.…

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March 9, 2022
Antimicrobial resistance and Population Genomics of Multidrug-resistant Escherichia coli in Pig Farms in Mainland China
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Antimicrobial resistance and Population Genomics of Multidrug-resistant Escherichia coli in Pig Farms in Mainland China

One of the most serious challenges to global public health is antimicrobial resistance (AMR). The advent and rapid spread of extensively drug-resistant (XDR), pandrug-resistant (PDR) bacteria and multidrug-resistant (MDR) particularly microorganisms resistant to last-resort antibiotics such as carbapenems, colistin, and tigecycline, has sparked widespread concern. Several drug-resistant bacteria are a…

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March 5, 2022
Discovery of Actinomycin L, A New Member of the Actinomycin Family of Antibiotics
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Discovery of Actinomycin L, A New Member of the Actinomycin Family of Antibiotics

Antibiotic resistance is the major emerging crisis that escalates among the pathogen. Hence newer, less toxic and efficient drugs remains the top priority. The majority source of antibiotics in use today is from Actinobacteria and the antibiotic identified is Actinomycin. Streptomyces’s is the crucial bioactive natural product producer that includes…

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March 3, 2022