New Antibiotics for Multidrug-Resistant Bacterial Strains: Latest Research Developments and Future Perspectives

Antibiotics are crown to the modern medicine, and they are the weapon against numerous infectious diseases. The exposure of bacteria to ‘non-lethal levels’ of antibiotics is causing antibiotic resistance (ABR) in them. Multidrug resistance (MDR) is the most common type of resistance. The MDR refers to bacteria showing resistance to…

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Governing Antimicrobial Resistance: A Narrative Review of Global Governance Mechanisms

Antimicrobial resistance (AMR), a central health challenge of the twenty first century, poses substantial population health risks, with deaths currently estimated to be around 700,000 per year globally. After implementing effective policy responses to AMR, with a Global Action Plan on AMR approved by the World Health Assembly in 2015.…

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Antimicrobial resistance and Population Genomics of Multidrug-resistant Escherichia coli in Pig Farms in Mainland China

One of the most serious challenges to global public health is antimicrobial resistance (AMR). The advent and rapid spread of extensively drug-resistant (XDR), pandrug-resistant (PDR) bacteria and multidrug-resistant (MDR) particularly microorganisms resistant to last-resort antibiotics such as carbapenems, colistin, and tigecycline, has sparked widespread concern. Several drug-resistant bacteria are a…

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Discovery of Actinomycin L, A New Member of the Actinomycin Family of Antibiotics

Antibiotic resistance is the major emerging crisis that escalates among the pathogen. Hence newer, less toxic and efficient drugs remains the top priority. The majority source of antibiotics in use today is from Actinobacteria and the antibiotic identified is Actinomycin. Streptomyces’s is the crucial bioactive natural product producer that includes…

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Global Burden of Bacterial Antimicrobial Resistance in 2019: A Systematic Analysis

Antimicrobial resistance (AMR) is a global health issue. The irrational use of antibiotics in human, animal and environment sectors give rise to AMR. Apprehensions are rife that AMR may follow similar patterns as seen in case of epidemic outbreaks developing into pandemics. In this situation, it becomes imperative to understand…

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Antibiotic Resistance in Wild Birds
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Antibiotic Resistance in Wild Birds

Wild birds have been identified as sentinels, reservoirs, and potential antibiotic resistance spreaders. A variety of antibiotic-resistant bacteria have been discovered from wild bird species. Several investigations have found that resistant bacteria are transmitted to wild birds by human rest products. There is evidence that wild birds can spread resistant…

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A Hot Topic at the Environment–Health Nexus: Investigating the Impact of Climate Change on Infectious Diseases

The climate change affects the social, economic and environmental determinants of health. It is the ultimate challenge of our times. Climate change is projected to impact both endemicity and prevalence of infectious diseases. Pathogen distribution, particularly the geographic and temporal distribution of vector-borne diseases like dengue and malaria, is expected…

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Synthetic Antibacterial Minerals: Harnessing a Natural Geochemical Reaction to Combat Antibiotic Resistance

The misuse and overuse of antibiotics in livestock and clinical settings is increasing the natural selection of multidrug-resistant bacteria. The resultant is antibiotic resistance bacteria along with the rise in mortality and financial burden on livestock and the healthcare industry. Hence, there is a need for novel strategies to deal…

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Eco-friendly Ways to Feed Pigs without Antibiotics

The health of the young piglet depends on the body’s resistance and immune status which is largely determined by the diet of the animal. If the diet is not taken properly, the pigs become very sensitive to the diseases caused by pathogens. Until recently, the most common way to fight…

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Contamination of Fresh Produce with Antibiotic-Resistant Bacteria and Associated Risks to Human Health: A Scoping Review

Daily intake of fruits and vegetables is necessary to fulfil the daily requirements of vitamins and minerals for human body. But, consuming them raw exposes us to many bacteria including the resistant ones. Different genera of drug resistant bacteria were identified from raw vegetables and fruits, the most common being…

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