Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials.

Antibiotic resistance is one of the global challenges which needs to be addressed immediately. Nowadays, antibiotic-resistant infections are not easily getting cured with conventional antibiotics and thereby causing havoc. This issue can be addressed by developing either new antimicrobials or strategies that will increase the efficiency of the current antimicrobials.…

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Antibiotic Resistance in Minimally Human-Impacted Environments

The presence of antibiotic-resistant bacteria (ARB) and resistant genes (ARG) in environments with close human contact like agriculture, wastewater effluent, etc are established through numerous studies across the globe. But studies focussing on the presence of ARB in minimally human-impacted areas/ pristine areas are very few. Minimally human-impacted environments are…

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Infections and antimicrobial resistance in intensive care units in lower-middle-income countries: a scoping review

Antimicrobial-resistance (AMR) is one of the quickly worsening problems worldwide. It affects all the countries, but the burden is alarmingly higher in lower-middle-income countries (LMICs). Approximately fifty countries belong to the LMIC category sharing the same bracket of Gross National Income, as per the World Bank update. Individuals admitted to…

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The use of non-prescribed antibiotics; prevalence estimates in low-and-middle-income countries. A systematic review and meta-analysis

Self-medication and over the counter medication are very common practice in low- and middle-income countries (LMICs) like India. The use of antibiotics without prescription is enlisted among the most important causes of antibiotic resistance (ABR). The unwise and frequent consumption of non-prescribed antibiotics (NPA) is persisting in LMICs where a…

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Primary care physicians’ attitudes and perceptions towards antibiotic resistance and outpatient antibiotic stewardship in the USA: a qualitative study

About 30% of the antibiotics prescribed in the outpatient setting is unnecessary. This injudicious use of antibiotics could propel the emergence and spread of antibiotic resistance. Outpatient antibiotic stewardship is one of the ways to monitor antibiotic prescription practices. But what are the attitudes and perceptions of primary care physicians…

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Antibiotic resistance surveillance systems: A review

The twentieth century was the 'golden age' of antibiotics for the extensive development and its use in humans and animals. The idea behind the discovery of antibiotics was to reduce suffering and deaths due to curable infectious diseases. However, such immense use of antibiotics had let to the selection of…

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IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance

Antibiotic resistance has devastating socioeconomic impacts globally. A plethora of alternatives to antibiotics are under investigation. Moreover, antimicrobial strategies that are less likely to develop resistance are immediately required to treat severe antibiotic-resistant infections.   Recently, a team of researchers led by Joseph M. Salvino & Farokh Dotiwala (The Wistar…

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Evaluation of the health and healthcare system burden due to antimicrobial-resistant Escherichia coli infections in humans: a systematic review and meta-analysis

Antimicrobial resistance (AMR) is a pressing global health issue that is jeopardizing the advances made by modern medicine. As per the report of the UN Interagency Coordination Group (IACG) released in 2019, drug resistance infections could cause 10 million deaths each year by 2050 and will damage the economy as…

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Global Trends in Antimicrobial Use in Food Animals from 2017 to 2030

The antimicrobial agents are used throughout the world across a diverse array of livestock, to protect their health and production. The rise in demand for animal protein is facilitated by intensive farming. Intensive farming involves high inputs such as capital, fertilizers, labor in relation to cultivating area along with medications…

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