A descriptive analysis of antimicrobial resistance patterns of WHO priority pathogens isolated in children from a tertiary care hospital in India

The Global Action Plan is one of the key initiatives by the World Health Organization (WHO) to combat the increasing incidence of antimicrobial resistance (AMR). In this direction, WHO has articulated a list of pathogens under the umbrella of ‘priority pathogens’ to provide strategic direction to research and develop new…

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Novel tool to visualize antibiotic resistance

Detection of antibiotic resistance gene (ARGs) and antibiotic-resistant bacteria (ARB) have become of utmost importance to decide a line of treatment for any bacterial infection. As the evidence-based use of antibiotics will reduce the misuse of antibiotics, detection of antibiotic -resistance is currently under investigation. The presence of the enzyme…

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Why do people purchase antibiotics over-the-counter? A qualitative study with patients, clinicians, and dispensers in central, eastern, and western Nepal

Antibiotic resistance is a global health priority. Many studies have pinpointed the causes and risk factors of the rising antibiotic resistance. Among the many causes identified, over-the-counter (OTC) use of antibiotics is one of the major causes, especially in low and middle-income countries like India, Nepal, Kenya, etc. Hence, it…

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The Application of Nanomaterials for the Electrochemical Detection of Antibiotics: A Review

Antibiotics are the entities that help us to fight against the bacterial infections. These antibiotics are being used as therapeutic agents in humans while as therapeutic, prophylactic as well as growth promoters in case of animals. The release of antibiotics in human and animal waste results in the entry of…

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Deciphering potential roles of earthworms in mitigation of antibiotic resistance in the soils from diverse ecosystems

Antibiotic resistance (ABR) is ‘one health’ challenge and it needs to be tackled with the one health approach. The injudicious use of antibiotics in human, animal and plant health has increased the abundance of antibiotic, antibiotic-resistant bacteria (ARBs) and antibiotic-resistant genes (ARGs) in the environment. It has been found that…

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Exploring the Antibiotic Resistance Burden in Livestock, Livestock Handlers and Their Non-Livestock Handling Contacts: A One Health Perspective

While the current World is dealing with the COVID-19 pandemic, another global health threat called “Antimicrobial resistance (AMR)” can’t be ignored. AMR is also an important zoonotic concern which has been enhances by the irrational use of antibiotic drugs in humans and domestic animals. Generally, antimicrobials are used in livestock…

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Antimicrobial resistance research in a post-pandemic world: Insights on antimicrobial resistance research in the COVID-19 pandemic

The COVID-19 (Coronavirus Disease 2019) pandemic is expected to impact bacterial infection transmission and the development of antimicrobial resistance (AMR). The confirmed overuse of broad-spectrum antibiotics to treat individuals infected with the coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) had impacted positively to cause AMR. In this regard, the…

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Cross-kingdom inhibition of bacterial virulence and communication by probiotic yeast metabolites

Probiotics are live microorganisms that upon consumption offer a plethora of health advantages. Fermented milk products e.g. yogurt, kefir are renowned for their health benefits. However, the mechanism behind their antimicrobial activity is yet elusive. Identifying the action of probiotics is essential to avail their maximum benefits and use them…

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Antibiotics and Antibiotic Resistance Genes in Animal Manure – Consequences of Its Application in Agriculture

It is an indisputable fact that antibiotic resistance (ABR) is on the rise. The major contributor to the increase in the ABR is the injudicious and widespread use of antibiotics in animals and agriculture. Antibiotic-resistant genes (ARG) compound the problem. The presence of bacteria resistant to last-line drugs in the…

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