Antimicrobial resistance (AMR), a central health challenge of the twenty first century, poses substantial population health risks, with deaths currently estimated to be around 700,000 per year globally. After implementing effective policy responses to AMR, with a Global Action Plan on AMR approved by the World Health Assembly in 2015. Suggestion in terms of combination of non-binding and binding governance mechanisms supported by leading antimicrobial using countries and key stakeholders in AMR, with One Health principles, may be best suited to tackle AMR.

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