One of the global challenges in the area of health is antimicrobial resistance, and it is urgent to rethink the use of antimicrobial drugs. The use of clinical and epidemiological methods to analyze the potential benefits and risks of drug therapy has now become a requirement for the rational use of drugs. Off-label use is the term utilized for the use of a drug other than that recommended and listed in the product registration and package insert. High rates of off-label use of these drugs in adult and paediatric patients have been reported. The objective of this study was to describe the off-label use of antibacterial in prescriptions for hospitalized adult patients as per the drug regulatory agency was studied and it was observed that off-label use of drugs is a frequent practice in the studied environment, and in the face of a dramatic scenario of increased antibacterial resistance.
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